Caenorhabditis elegans neurons under stress can produce giant vesicles. several microns in diameter. called exophers. Current models suggest that exophers are neuroprotective. https://www.morehartandweinman.com/product-category/kids-footwear/
Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell
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